Oprah

In a somewhat unexpected pairing (at least to me), Oprah Winfrey and Diablo Cody are teaming up for an HBO comedy, which will be based on an upcoming book by Dr. Julie Holland, titled Moody Bitches.

Diablo Cody

HBO’s logline for the show says that it “exposes the truth about the drugs you’re taking, the sex you’re not having, the sleep you’re missing and what’s really making you crazy,” which also happens to be the subtitle of the book by Dr. Holland - a psychiatrist and author of the best-selling autobiography, Weekends at Bellevue: Nine years on the NIght Shift at the Psych ER

Diablo Cody will write the pilot episode adapted from Holland's non-fiction book, and will executive produce alongside Oprah Winfrey, while Dr. Holland will co-executive produce.

Here's how the author describes Moody Bitches:

Women are naturally emotional, empathic creatures. There is a growing trend for women to medicate away their naturally fluctuating emotions, but as a psychiatrist and psychopharmacologist, I have learned; the further away we take ourselves from what is natural, the more problems we have. We should be outside, reveling in nature, following the rhythms of the moon and seasons, part of hunting/gathering clans. Instead, we’re inside with computers all day, sunlight deprived, cardio-starved, and socially isolated. We take antidepressants and anti-anxiety medications to cope, but there is a better way. A return to what is natural for us as primates is a prescription for happiness and ease.

This marks the first collaboration between Oprah and Cody, and maybe not the last.

No ETA yet on delivery, or whether the series will retain the title of the book.