Aykroyd told Larry King, on his "Larry King Now" show (via Bloody Disgusting), that "it's based on new research that's being done in particle physics by the young men and women at Columbia University," Aykroyd told King, who is almost old enough to play a mummy in the new movie. "Basically, there's research being done that I can say that the world or the dimension that we live in, our four planes of existence, length, height, width and time, become threatened by some of the research that's being done. Ghostbusters -- new Ghostbusters -- have to come and solve the problem."
Um. Okay. It's nice they're keeping the academia aspect of the series in place, as this was one of the more original and relatable aspects of the first film. Plus we all know how surefire a blockbuster movie centered around knotty, hard-to-decipher physics is. Because the kids love physics.
Anyway, Aykroyd did confirm that Bill Murray will not be returning for another ghost-busting go-around. "There will be a hole for him. If Billy wants to walk in the door and be in the movie, we will find a place." In other words: don't hold your breath.
Supposedly the script for "Ghostbusters 3" has been worked on by Gene Stupnitsky, Lee Eisenberg and Etan Cohen, and original director Ivan Reitman is still attached to helm, with a summer 2014 release date loosely bandied about to coincide with the original film's 30th anniversary, but honestly we're more likely to be slimed than to have this thing actually come out.