Set in the 1960s, James Franco (kinda looking a bit like Joaquin Phoenix from "The Master" in that pic above) plays a former actor and schizophrenic who lives with his mentally detached sister Patricia (Fallon Goodson) and his cross-dressing best friend (Keener) in the same house. And as you can guess, their lifestyle, coupled with their issues, ruffles more than a few feathers both inside and outside of the house as they try to make sense of their lives.
The movie is directed by the singularly named Carter, whose previous effort was something called "Erased James Franco," which featured the actor re-interpreting scenes from his own movies and Julianne Moore's role in "Safe." WUT? We should be catching this in Berlin, so stay tuned for a review. And "Maladies" arrives at SXSW next in March, so until then, watch below.