Guardian: "At 163 minutes Cloud Atlas carries all the marks of a giant folly, and those unfamiliar with the book will be baffled. Yet it's hard to wholly condemn the directors' ambition - this is fast-paced and cleverly assembled, with the best of the performances shining through the prosthetics (Hugh Grant makes great play of the clutch of villains he's dealt). The Tykwer/Wachowski collective offer everything here. Chances are there's something in the hodgepodge for you."
HitFix: "These stories push moral and ethical buttons in some unusual and even oblique ways, and there is plenty of room in the film for every viewer to have a different experience with what they see. There's a sense of trust on the part of the filmmakers that the audience will be willing to work for the pleasures that are strewn throughout, and there's also a deeply heartfelt optimism even in the film's darkest moments that makes it stand apart from the typical dystopian vision of most modern science fiction."