Michael Sheen and Lizzy Caplan in Showtime's "Masters of Sex"

The first season of Showtime's "Masters of Sex" received five Emmy nominations last month, including Lead Actress (Lizzy Caplan) and Guest Actress (Allison Janney). Can the series' excellent sophomore run, currently airing Sunday nights at 10, boost its chances of winning?

Developed by Michelle Ashford from Thomas Maier's eponymous dual biography, "Masters of Sex" follows respected ob-gyn Dr. William Masters (Michael Sheen) and secretary-turned-collaborator Virginia Johnson (Caplan, at once winsome and ferocious) as they embark on a controversial study of sexuality in late-1950s St. Louis. As the pair collects physiological data from human subjects in flagrante and defends against attacks by a conservative, male-dominated medical community, "Masters of Sex" also emerges as tale of kindred spirits. Bill and Virginia are both, in their own way, sexual revolutionaries, and watching them navigate each other, as well as their society's hidebound mores, is an unassuming joy.

At times the series is so unassuming, in fact, that the first season may not register with Emmy voters as potently as its more, shall we say, eager rivals. Don't get me wrong: for all the electrodes and unflattering fluorescents, "Masters of Sex" musters more erotic charge than any whorehouse in Westeros. But the series' ample charms won me over slowly, as the supporting characters blossomed and the protagonists eased into their delicate attraction, and it wasn't until Caplan's breathtaking fairground rendition of "You Don't Know Me," in the first season's penultimate episode, that I dove head first into love. (Watch the clip below.)

Caplan faces stiff competition in the Lead Actress category -- TOH! predicts Robin Wright to win for "House of Cards" -- but the sheer force of season two may persuade Television Academy members to give "Masters of Sex" another look. (Spoilers ahead if you're not caught up.) With Dr. Masters no longer employed by Washington University, the center of gravity shifts to Memorial Hospital, where the rich new husband (Greg Garber) of former prostitute Betty DiMello (Annaleigh Ashford) secures a place for the study by dint of a large donation, and the Chancery Park Plaza Hotel, where Bill and Virginia carry on with the "work" of their burgeoning affair.

"Parallax," the season premiere, flashes back to their first off-hours rendezvous, in which the useful fiction of contributing to science by having sex with each other briefly fell away, but it's the final scene that most clearly expresses their distinct perspectives. Bill intellectualizes the spark between them ("a second line of inquiry," he calls it), forgetting that Virginia's humane intuition is his only conduit to the messy world in which sex operates. The expression that flickers across her face, half wounded and half steely, functions in turn as a reminder of the series' credo: there's value to be found in all kinds of intelligence.