The trailer for the movie (which opens November 24) is below:
I have long wished that Zwick would head in a James L. Brooks direction into smart relationship comedy/drama territory. At last he seems to be bringing some of that laser sensibility to Love and Other Drugs, which stars Jake Gyllenhaal as a cocky drug salesman on a career high from the success of viagra, and the sharp woman who has his number (Anne Hathaway). Tragedy ensues (spoiler alert!) in the form of a debilitating disease (paging Love Story). It is one of the trickiest high-wire acts to pull off--asking the audience to laugh one minute, cry the next, while never losing believability.